Dr Oby Coucou Foundation Official CrestDr Oby CoucouFoundation
SCIENTIFIC MONOGRAPH & ARCHIVE

Scientific Publications & Clinical Research

“Advancing cardiometabolic medicine, vascular biomarkers, hypertension control, and stroke mitigation through rigorous, peer-reviewed global inquiry.”

As an accomplished Consultant Cardiologist and physician-scientist, Dr Obiageli Uzoamaka Onyemelukwe (MBBS, MSc, FCAI, MEMSON, FWACP) A.K.A Dr Oby Coucou has contributed to over 70 international peer-reviewed scientific publications. Her investigations bridge clinical practice, biochemical epidemiology, and community health trials.

* Note: Her research is indexed globally under both academic names: Obiageli Uzoamaka Onyemelukwe and Obiageli Uzoamaka Agbogu-Ike.

Distinguished Conference Recognition:

Awarded 3rd Best Abstract in Endocrine and Metabolic Scientific Conference

Honoring breakthrough clinical research in neurohormonal biomarker interactions and cardiometabolic syndrome in African patients.

ORCID ID: 0000-0002-3274-3154ResearchGate ProfileFounder Biography
Dr Obiageli Onyemelukwe — Physician-Scientist & Cardiologist

[ SCHOLARLY AUTHORITY ]

Dr Obiageli Uzoamaka Onyemelukwe

FELLOWSHIPS & ACCREDITATIONS

MBBSMScFCAIMEMSONFWACP

RESEARCH AFFILIATION

PENKUP Research Institute

Birmingham, United Kingdom

Published Corpus:Over 70 Papers
Network:SIREN Stroke Consortium
Core Subspecialty:Cardiovascular & Metabolic

SHOWING 23 OF 23 PEER-REVIEWED PAPERS

Complete Scientific Corpus

PUB-012019Heart Failure & Hemodynamics

B-Type Natriuretic Peptides (BNP) and Tissue Doppler E/e´ Before and After 4 Weeks Standard Treatment of African Heart Failure Subjects: The ABU-BNP Longitudinal Survey

Authors:Onyemelukwe OU, Oyati AI, Danbauchi SS, Obasohan AO.

Vascular Health and Risk ManagementVol: 15:523-535DOI: 10.2147/VHRM.S228221

Longitudinal investigation into tissue Doppler imaging parameters and ventricular filling pressures among Nigerian heart failure patients undergoing structured guideline therapy.

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PUB-022020ABU-BNP Survey

Relations of Plasma B-Type Natriuretic Peptides (BNP) to Tissue Doppler E/e´, Left Ventricular Systolic Functions and BNP Predictors in African Heart Failure Subjects: The ABU-BNP Survey

Authors:Onyemelukwe OU, Oyati AI, Danbauchi SS, Obasohan AO.

International MedicineVol: 2(1):50-60DOI: 10.5455/im.65435

Evaluation of neurohormonal biomarker correlations with echocardiographic diastolic dysfunction and systolic strain predictors in sub-Saharan African cardiac patients.

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PUB-032020Hypertension & Homocysteine

Relationship Between Plasma Homocysteine and Blood Pressure in Hypertensive Northern-Nigerians

Authors:Onyemelukwe OU, Maiha BB, Oyati AI, Danbauchi SS.

African Health SciencesVol: 20(1):324-337DOI: 10.4314/ahs.v20i1.38

Pioneering survey examining the vascular biomarker homocysteine and its direct correlation with blood pressure staging in Northern Nigerian hypertensives.

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PUB-042020ABU Homocysteine Survey

Prevalence of Hyperhomocysteinaemia, Selected Determinants and Relation to Hypertension Severity in Northern-Nigerian Hypertensives: The ABU Homocysteine Survey

Authors:Onyemelukwe OU, Maiha BB.

Ghana Medical JournalVol: 54(1):17-29DOI: 10.4314/gmj.v54i1.4

Investigating the high burden of hyperhomocysteinemia, independent dietary risk factors, and accelerated vasculopathy in primary hypertensive patients.

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PUB-052019Vascular Biomarkers

Hyperhomocysteinemia and Folate Levels in Normal Healthy Nigerians Living in Zaria: Subanalysis of ABU Homocysteine Cross-sectional Survey

Authors:Onyemelukwe OU, Maiha BB.

Annals of African MedicineVol: 18(3):143-152DOI: 10.4103/aam.aam_53_18

Baseline normative range survey of homocysteine and folate parameters among healthy Nigerian populations to establish regional clinical reference boundaries.

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PUB-062020Diabetes & Cardiometabolic

Leptin Concentrations in Type 2 Diabetes and Non-Diabetes Nigerian-Africans

Authors:Onyemelukwe OU, Ogoina D, Onyemelukwe GC.

American Journal of Cardiovascular DiseaseVol: 10(4):444-454PMID: 33224595PMCID: PMC7675163

Comparative endocrine evaluation demonstrating altered adipokine signalling and cardiometabolic dysregulation between diabetic and non-diabetic African subjects.

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PUB-072020Obesity & Metabolism

Leptin Concentrations in Non-Obese and Obese Non-Diabetes Nigerian-Africans

Authors:Onyemelukwe OU, Ogoina D, Onyemelukwe GC.

Diabetes, Metabolic Syndrome and Obesity: Targets and TherapyVol: 13:4627-4638DOI: 10.2147/DMSO.S264735

Demonstrating hyperleptinemia in visceral adiposity independent of diabetic status in indigenous West African populations.

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PUB-082020ABUTH Occupational Survey

Prevalence of Pre-Diabetes, Diabetes and Associated Cardiovascular Risk Amongst Healthcare Workers in Ahmadu Bello University Teaching Hospital (ABUTH), Zaria Using Glycated Haemoglobin

Authors:Onyemelukwe OU, Mamza AA, Suleiman YK, Iyanda MA, Bello-Ovosi B, Bansi KI, Adeleye AO, Balarabe H, Ahmed MS, Okpe IO, Bello F, Bakari AG.

West African Journal of MedicineVol: 37(2):91-99PMID: 32150625

Major occupational health epidemiological study assessing hidden glycemic dysregulation and metabolic cardiovascular risk profiles in tertiary healthcare personnel.

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PUB-092022Endocrine & Adipokines

Effect of Obesity on Resistin Concentrations in Normal, Pre-Obese and Obese Apparently Healthy Nigerian-Africans

Authors:Onyemelukwe OU, Ogoina D, Onyemelukwe GC.

West African Journal of MedicineVol: 39(7):791-802PMID: 33402920PMCID: PMC7750072

Investigating resistin cytokine levels across progressive BMI categories and establishing its association with subclinical cardiovascular inflammation.

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PUB-102022Occupational Cardiovascular Health

Pre-Obesity/Obesity in Relation to Blood Pressure Among Tertiary Healthcare Workers in an African Setting

Authors:Onyemelukwe OU, Kaoje YS, Isa BK, Mamza AA, Iyanda MA, Bello-Ovosi B, Adeleye AO, Balarabe H, Ahmed M, Okonkwo LO, Okpe IO.

African Journal of Endocrinology and MetabolismVol: 12(1):28-40DOI: 10.4103/ajem.ajem_12_22

The study aimed to determine the predictive power of pre-obesity/obesity indices in pre-hypertension and hypertension among tertiary healthcare workers in Northern Nigeria.

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PUB-112019Clinical Cardiology Registry

Clinical Echocardiographic and Laboratory Spectrum in African Heart Failure: Findings from the Northern Nigerian Registry

Authors:Onyemelukwe OU, Danbauchi SS, Oyati AI.

Journal of Cardiovascular Disease Research (JCDR)Vol: 10(1):35-46DOI: 10.5530/jcdr.2019.1.7

Detailed structural analysis of left ventricular dimensions, valvular patterns, and neurohormonal profiles in hospitalized heart failure cohorts.

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PUB-11B2018Clinical Trials & Vascular

Randomised Double-Blind Placebo-Controlled Study of Folic Acid Adjunct for 8 Weeks in Hyperhomocysteinaemic Hypertensive Patients in Zaria, Nigeria

Authors:Onyemelukwe OU, Maiha BB, Ayanwuyi LO, Dahiru T.

Journal of Drug Delivery and TherapeuticsVol: 8(5):338-348DOI: 10.22270/jddt.v8i5.1879

Demonstrating short-term daily folic acid supplementation effect on homocysteine reduction in hypertensive subjects.

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PUB-122026Community Epidemiology

Correlates of Knowledge and Treatment of Hypertension in a Semi-Urban Community in Nigeria

Authors:Onyemelukwe OU, et al.

The USA Journals (IJSSHD)Vol: 3(7):24-35DOI: 10.55640/ijsshd-v03i07-04

Community survey exploring health literacy barriers, treatment compliance, and blood pressure control rates in transitional peri-urban environments.

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PUB-132026Occupational Health

Occupational Health Risks, Safety Practices, and Institutional Gaps among Histopathologists in Nigeria: Evidence from a Nationwide Cross-Sectional Study

Authors:Onyemelukwe OU, et al.

International Journal of Medical Science and Clinical Research StudiesVol: 6(7):102-114DOI: 10.37547/ijmscr/Volume06Issue07-01

Controlled intervention study demonstrating occupational health risks and institutional gaps among histopathologists in Nigeria.

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PUB-142026Rural Health Outreach

Prevalence of Hypertension and Its Risk Factors in a Rural Community in Nigeria

Authors:Onyemelukwe OU, et al.

The American Journal of Medical Sciences and Pharmaceutical ResearchVol: 8(8):45-58DOI: 10.37547/tajmspr/Volume08Issue08-05

Uncovering previously undiagnosed hypertension burdens in remote communities with recommendations for mobile health screening integration.

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PUB-152026Lifestyle Medicine

Evaluating the Impact of Lifestyle Modifications on Blood Pressure Control in Hypertensive Patients

Authors:Onyemelukwe OU, et al.

Frontiers in Medical Case ReportsVol: 3(7):15-28DOI: 10.64917/fmcs/Volume03Issue07-01

Evaluating dietary sodium restriction, potassium enrichment, and physical activity prescriptions in non-pharmacological blood pressure management.

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PUB-162026Stroke Rehabilitation

Prevalence and Sociodemographic Profile of Caregiver Strain Among Caregivers of Stroke Survivors in Oyo State, Nigeria

Authors:Onyemelukwe OU, et al.

International Journal of Modern MedicineVol: 5(4):78-90DOI: 10.55640/ijmm-05-04-08

Assessment of psychological, physical, and financial strain on primary family caregivers of stroke survivors, highlighting urgent welfare support needs.

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PUB-172022SIREN Consortium

Determinants of Metabolic Syndrome and Its Prognostic Implications Among Stroke Patients in Africa: Findings from the Stroke Investigative Research and Educational Network (SIREN) Study

Authors:Adeoye AM, Akintunde AA, Akinyemi J, Fakunle AG, Sarfo FS, Akpalu A, Wahab K, Obiako R, Komolafe M, Owolabi L, Osaigbovo GO, Akpa O, Arulogun O, Okekunle AP, Ogah OS, Jenkins C, Ogbole G, Tiwari HK, Asowata OJ, Ibinaiye P, Appiah L, Agunloye AM, Yaria J, Calys-Tagoe B, Agbogu-Ike OU, Adeniyi S, Adebayo P, Balogun O, Aderonmu O, Adeegbe OT, Adebayo O, Akinyemi R, Ovbiagele B, Owolabi M; SIREN.

Journal of the Neurological SciencesVol: 441:120360DOI: 10.1016/j.jns.2022.120360PMID: 35985161

Pan-African multi-center study investigating the fatal prognostic role of metabolic syndrome clusters in stroke recovery across West Africa.

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PUB-182023Stroke Severity Predictors

Determinants of First-Ever Stroke Severity in West Africans: Evidence From the SIREN Study

Authors:Adebayo O, Akpa O, Asowata OJ, Fakunle A, Sarfo FS, Akpalu A, Wahab K, Obiako R, Komolafe M, Owolabi L, Osaigbovo GO, Okekunle AP, Sunmonu T, Tiwari HK, Jenkins C, Arulogun O, Appiah L, Akinyemi J, Adeoye AM, Ogbole G, Yaria J, Arnett D, Adebayo P, Calys-Tagoe B, Ogah OS, Balogun O, Ogunjimi L, Mensah Y, Agbogu-Ike OU, Akinyemi R, Ovbiagele B, Owolabi MO; SIREN.

Journal of the American Heart Association (JAHA)Vol: 12(12):e027888DOI: 10.1161/JAHA.122.027888PMID: 37301737PMCID: PMC10356032

Multi-center investigation evaluating neurological stroke severity scores and baseline clinical predictors among native West African patients.

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PUB-192024Intracerebral Hemorrhage

Clinical and Neuroimaging Factors Associated with 30-Day Fatality Among Indigenous West Africans with Spontaneous Intracerebral Hemorrhage

Authors:Komolafe MA, Sunmonu T, Akinyemi J, Sarfo FS, Akpalu A, Wahab K, Obiako R, Owolabi L, Osaigbovo GO, Ogbole G, Tiwari HK, Jenkins C, Lackland DT, Fakunle AG, Uvere E, Akpa O, Dambatta HA, Akpalu J, Onasanya A, Olaleye A, Ogah OS, Isah SY, Fawale MB, Adebowale A, Okekunle AP, Arnett D, Adeoye AM, Agunloye AM, Bello AH, Aderibigbe AS, Idowu AO, Sanusi AA, Ogunmodede A, Balogun SA, Egberongbe AA, Rotimi FT, Fredrick A, Akinnuoye AO, Adeniyi FA, Calys-Tagoe B, Adebayo P, Arulogun O, Agbogu-Ike OU, Yaria J, Appiah L, Ibinaiye P, Singh A, Adeniyi S, Olalusi O, Mande A, Balogun O, Akinyemi R, Ovbiagele B, Owolabi M; SIREN.

Journal of the Neurological SciencesVol: 458:122848DOI: 10.1016/j.jns.2023.122848

Identifying neuroimaging hallmarks and clinical markers directly predicting early post-stroke fatality in acute hemorrhagic stroke cohorts.

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PUB-202024Hypertension & Stroke Risk

Stroke Occurrence by Hypertension Treatment Status in Ghana and Nigeria: A Case-Control Study

Authors:Sarfo FS, Asowata OJ, Akpa OM, Akinyemi J, Wahab K, Singh A, Akpalu A, Opare-Addo PA, Okekunle AP, Ogbole G, Fakunle A, Adebayo O, Obiako R, Akisanya C, Komolafe M, Olunuga T, Chukwuonye II, Osaigbovo G, Olowoyo P, Adebayo PB, Jenkins C, Bello A, Laryea R, Ibinaye P, Olalusi O, Adeniyi S, Arulogun O, Ogah O, Adeoye A, Samuel D, Calys-Tagoe B, Tiwari H, Obiageli O, Mensah Y, Appiah L, Akinyemi R, Ovbiagele B, Owolabi M.

Journal of the Neurological SciencesVol: 459:122968DOI: 10.1016/j.jns.2024.122968PMID: 38518449PMCID: PMC11073807

Quantifying the heightened protective odds of regular antihypertensive therapy versus irregular adherence across multi-center West African cohorts.

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PUB-212023Dietary Risk & Stroke

Dietary Patterns Associated with Stroke Among West Africans: A Case-Control Study

Authors:Akinkunmi P Okekunle, Osahon Asowata, Onoja M Akpa, Bruce Ovbiagele, Adekunle Fakunle, Morenikeji Komolafe, Oyedunni Arulogun, Fred S Sarfo, Albert Akpalu, Reginald Obiako, Kolawole Wahab, Godwin Osaigbovo, Lukman Owolabi, Godwin Ogbole, Joshua Akinyemi, Sunday Adeniyi, Benedict Calys-Tagoe, Mayowa Aridegbe, Akintunde Adebowale, Hamisu Dambatta, Atinuke Agunloye, Olalekan Oyinloye, Adeniyi Aderibigbe, Isah Suleiman, Abiodun M Adeoye, Josephine Akpalu, Obiageli Agbogu-Ike, Hemant K Tiwari, Donna Arnett, Rufus Akinyemi, and Mayowa O Owolabi on behalf of SIREN as part of the H3Africa consortium.

International Journal of StrokeVol: 18(2):193-200DOI: 10.1177/17474930221094933PMID: 35377255

Nutritional epidemiological research examining specific dietary food combinations and their protective versus deleterious correlation with stroke risk.

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PUB-222025Cerebrovascular Pharmacology

Antecedent Sedative Use is Independently Associated with Stroke Occurrence Among West Africans: Evidence from the SIREN Case-Control Study

Authors:Uvere EO, Akinyemi J, Sarfo FS, Fakunle A, Okekunle AP, Akpa O, Akpalu A, Wahab K, Obiako R, Komolafe M, Owolabi L, Osaigbovo GO, Ogbole G, Tiwari HK, Jenkins C, Olowookere S, Arulogun O, Akpalu J, Asowata OJ, Ibinaiye P, Akisanya C, Oyinloye OI, Appiah L, Agunloye AM, Adeoye AM, Yaria J, Lackland DT, Arnett D, Laryea RY, Calys-Tagoe B, Ogah OS, Ogunronbi M, Isah SY, Dambatta HA, Tagge R, Balogun O, Agbogu-Ike OU, Akinyemi R, Ovbiagele B, Owolabi M; SIREN.

eNeurologicalSciVol: 40:100573DOI: 10.1016/j.ensci.2025.100573PMID: 40599698PMCID: PMC12209909

Pioneering multicenter discovery linking chronic unprescribed sedative use with increased susceptibility to acute cerebrovascular episodes.

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INDEXING & REPOSITORIES

International Repository Access & Archives

Dr. Onyemelukwe's published clinical surveys and trials are indexed across major global medical databases, clinical libraries, and research networks.

NIH / PubMed Central

National Institutes of Health (NIH) & Europe PMC

Public biomedical repository indexing full PMC and PubMed cardiovascular clinical texts.

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Taylor & Francis

Taylor & Francis Online Medical Journals

Peer-reviewed cardiovascular clinical research, metabolic therapy, and drug delivery.

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ScienceDirect

ScienceDirect / Elsevier Clinical Journals

Journal of the Neurological Sciences and international neurological stroke studies.

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The USA Journals

The USA Journals & International Academic Publishing

Epidemiological surveys on hypertension literacy, lifestyle modification, and rural health.

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e-Century

e-Century Publishing Corporation

Publisher of the American Journal of Cardiovascular Disease and endocrine reports.

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